Cetirizine hydrochloride is a drug (mostly known under the brand name Zyrtec) that is used in the treatment of allergies, hay fever, angioedema and urticaria. It is a second-generation H1-receptor antagonist (antihistamine) and acts by means of the blocking of histamine H1 receptors. It is a major metabolite of hydroxyzine, and has the same side effects including dry mouth. Since 2001, many users of cetirizine switched to levocetirizine.
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