Magnetize brain cell to guide and improve the performance of traditional cell therapy for ischemic stroke. This is the process syndrome d asperger in which new equipment Institut de Ciencia de Materials de Barcelona-CSIC, led by Anna Roig, and the group of Neurorepair Neurovascular Research Laboratory delInstituto Research Hospital Vall d'Hebron, led by Anna work Rosell.
Ischemic stroke is caused by occlusion of a cerebral artery and represents about 90% of the 15 million strokes that occur in the world each year. And it is estimated that of all concerned, five million die and another five left with some permanent neurological deficit. syndrome d asperger Currently no neuroreparadores treatments to regenerate damaged tissue and restore lost functions. The only neuroprotective treatment for patients diagnosed with ischemic stroke is the administration of Tissue Plasminogen Activator (tPA) for clot dissolution that caused the stroke. But this treatment should be administered in the acute phase of the disease, in the first four hours of the onset of symptoms.
Cell therapy is to treat a disease by reaching certain cells in tissues affected by the disease to regenerate damaged tissue. The process we have developed teams led by Roig and Rosell pursues the creation of new blood vessels from growth factors secreted by endothelial cells accumulated in this part of the brain. For this purpose cells are cultured with colloidal solutions of iron oxide nanoparticles (of about 6 nm in diameter) around the clock without affecting its functionality. Cells endocytosed particles in sufficient amounts such that when administered systemically to the patient can be attracted by an external syndrome d asperger magnetic field produced by a small permanent magnet. Thus, accumulating is achieved in the area of the brain affected by ischemic stroke. The ultimate goal is a neuroreparador treatment with subsequent syndrome d asperger functional recovery of the affected part of the brain.
Research of Vall d'Hebron and the Institut de Ciencia de Materials, a specialist in the development of nanomaterials syndrome d asperger to apply inter alia to biomedicine and nanomedicine center, syndrome d asperger is very innovative, not only in Spain but worldwide. "Very few groups specifically for this purpose cell therapy used in synergy with nanomaterials," syndrome d asperger says Anna Roig.
The research, which is currently at a preclinical stage, is the result of four years of intense syndrome d asperger work. The treatment has already been tested on animals with "very promising" results, syndrome d asperger although there are still a few years so you can reach the clinical phase. Much depends on the funding that have, so far has been very limited, which has meant that everything goes slower than they would like. "The duration is associated with the money one has to investigate. And now is a time when finance is a touchy subject. But we are very happy to launch research how "he says.
As one of the groups least valued by the institutions and the business and severely affected by the economic crisis, most inventors, innovators and Spanish researchers struggle every day to survive in the domestic market, while others have no choice but to put distance in between and move to other countries in search of better opportunities.
Groups, in close collaboration with the Spanish Association of Inventors, starts this section syndrome d asperger with the aim to serve as a showcase for the disclosure of the wealth flowing in Spain ideas. Our ingenious inventors syndrome d asperger are innovative, but also brave entrepreneurs, capable of generating syndrome d asperger employment and wealth. Many ideas are on paper, but most deserve become reality syndrome d asperger and become an exportable product.
If you are an inventor syndrome d asperger and you want your projects are known to send a proposal to the will value eureka@publico.es by the Spanish Association of Inventors. If selected sale we will contact you for publication.
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