But often we think that there are differences in our response to medication. The medication that works for you may not work on me and the right dose of a drug can be very individual in nature.
"It is a problem for the patients who are not getting the optimal dose of a drug, and it costs society money because patients who do not respond as desired, run the risk of a prolonged illness," explains senior scientist Henrik Berg Rasmussen, nasal polyps Department of Biology Psychiatry at St. His.
"In psychiatry, you try often with various doses until you find the right one, but it is not optimal, such as Ritalin are drugs you have to be careful," said Henrik Berg Rasmussen.
If the fabric breaks down too quickly, there is not the correct concentration nasal polyps of the substance in the body. Today it is estimated that 20-25% patients of the patients started on treatment for ADHD with Ritalin does not respond to the drug and therefore requires an effective treatment for patients that switching to another drug. The substance decomposes too slowly, nasal polyps the patient risks accumulation of the substance nasal polyps in the body, and thus the risk of side effects. In the case of Ritalin, a patient may experience side effects such as growth retardation, difficulty sleeping or stomach cramps. nasal polyps It may also rarely cause psychosis. Precise categories
35 healthy people should nasal polyps take the drug Ritalin. Next, the researchers will conduct a genetic analysis of the subjects. The same experiment done with a medicine for heart disease.
The researchers will, in the light of the results could construct a number of categories for people with fast, normal nasal polyps or slow enzyme activity in the liver. These categories can be used to ensure that patients receive nasal polyps the right dose of medicine.
The enzyme CES 1 degrades not only Ritalin and medication for heart disease, but also a number of other medicines. They include flu drug Tamiflu and certain types of cancer therapeutics.
The researchers will include ogå examine the interaction between different types of medication nasal polyps because a variety of diseases, such as ADHD, often seen with other diagnoses. Therefore, patients may, for example, both have medication for depression and ADHD at the same time.
"I have been very fortunate to know a team of talented people in various fields and this means that our research has the option to be used very widely," says Henrik Berg Rasmussen.
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